Cardiovascular Gastro/Intestinal Gynecology Neuro Orthopedics Ophthalmology Pulmonary Urology Vascular

Circe Biomedical, Inc. is a cell therapy company developing a bioartificial liver for treatment of patients with acute liver failure. The company is presently engaged in a multicenter pivotal Phase II/III trial, aimed at demonstrating improved survival in patients with Fulminant Hepatic Failure, a specific form of acute liver failure. Acquired by Valient Pharmaceuticals. (NYSE: VEX) April 4, 2002 Endonetics is focused on the development of endoscopic devices for gastrointestinal reflux disease (GERD). The Company is developing two proprietary endoscopic technologies, one diagnostic and one therapeutic, that will have significant impact on the gastroenterologist's ability to manage patients with GERD. Acquired by Medtronic, Inc. (NYSE:MDT): December 2001. Leptos is focused on developing a nerve stimulation therapy for the treatment of obesity.